
Congo Red
CAS No. 573-58-0
Congo Red ( Direct Red 28 )
产品货号. M24566 CAS No. 573-58-0
刚果红是一种偶氮染料。它的结合被用作组织切片中淀粉样蛋白存在的诊断测试。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥575 | 有现货 |
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1G | ¥867 | 有现货 |
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生物学信息
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产品名称Congo Red
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述刚果红是一种偶氮染料。它的结合被用作组织切片中淀粉样蛋白存在的诊断测试。
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产品描述Congo Red is an azo dye. It binding been used as a diagnostic test for the presence of amyloid in tissue sections.
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体外实验Congo Red histochemical stain may serve as a simple screening tool for investigating if the aggregates in mutant cells have misfolded β-pleated sheet secondary structures. Congo Red histochemical dye has the ability to bind specifically to crossed β-pleated sheet structures. Wild-type HSPB1 should maintain protein homeostasis by binding proteins in non-native conformations, thereby preventing substrate aggregation. The T139M mutant, however, fails in this function and results in an accumulation of misfolded proteins, which are targeted by Congo Red for intercalating between the β-pleated sheet structures. Congo Red histochemical stain may serve as a simple tool to investigate if the aggregates in mutant cells have misfolded β-pleated sheet secondary structures.
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体内实验——
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同义词Direct Red 28
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number573-58-0
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分子量696.66
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分子式C32H22N6Na2O6S2
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纯度>98% (HPLC)
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溶解度DMSO:100 mg/mL (143.54 mM;Need ultrasonic)
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SMILESNc(c1ccccc1c(S([O-])(=O)=O)c1)c1N=Nc(cc1)ccc1-c(cc1)ccc1N=Nc(cc(c1ccccc11)S([O-])(=O)=O)c1N.[Na+].[Na+]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Amornvit J, et al. A novel p.T139M mutation in HSPB1 highlighting the phenotypic spectrum in a family. Brain Behav. 2017 Jul 21;7(8):e00774.
产品手册




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